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Marcella Rietschel Selected Research

Nortriptyline (Aventyl)

1/2019Effect of antidepressant switching between nortriptyline and escitalopram after a failed first antidepressant treatment among patients with major depressive disorder.
1/2019Trajectories of Suicidal Ideation During 12 Weeks of Escitalopram or Nortriptyline Antidepressant Treatment Among 811 Patients With Major Depressive Disorder.
10/2018Genetic disposition to inflammation and response to antidepressants in major depressive disorder.
1/2016Combining clinical variables to optimize prediction of antidepressant treatment outcomes.
4/2011Changes in body weight during pharmacological treatment of depression.
12/2010Stressful life events, cognitive symptoms of depression and response to antidepressants in GENDEP.
6/2010History of suicide attempts among patients with depression in the GENDEP project.
11/2009Body weight as a predictor of antidepressant efficacy in the GENDEP project.
11/2009Genetic predictors of increase in suicidal ideation during antidepressant treatment in the GENDEP project.
10/2009Suicidal ideation during treatment of depression with escitalopram and nortriptyline in genome-based therapeutic drugs for depression (GENDEP): a clinical trial.
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Marcella Rietschel Research Topics

Disease

91Schizophrenia (Dementia Praecox)
10/2022 - 04/2002
38Bipolar Disorder (Manic Depressive Psychosis)
07/2022 - 04/2002
21Alcoholism (Alcohol Abuse)
11/2021 - 07/2008
20Mood Disorders (Mood Disorder)
01/2021 - 07/2002
18Major Depressive Disorder (Major Depressive Disorders)
04/2022 - 02/2005
13Mental Disorders (Mental Disorder)
01/2021 - 01/2004
9Psychotic Disorders (Schizoaffective Disorder)
01/2022 - 11/2008
8Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
01/2018 - 04/2007
7Genetic Risk Score
07/2022 - 01/2017
6Alzheimer Disease (Alzheimer's Disease)
01/2021 - 04/2012
6Depressive Disorder (Melancholia)
01/2020 - 09/2008
4Drug-Related Side Effects and Adverse Reactions
12/2021 - 09/2009
4Substance-Related Disorders (Drug Abuse)
01/2020 - 08/2013
4Inflammation (Inflammations)
10/2018 - 05/2017
3Wounds and Injuries (Trauma)
01/2022 - 01/2018
3Sleep Deprivation
01/2020 - 12/2018
3Obesity
12/2017 - 11/2009
3Tobacco Use Disorder (Nicotine Dependence)
03/2016 - 08/2010
3Body Weight (Weight, Body)
03/2013 - 11/2009
3Sleep Initiation and Maintenance Disorders (Insomnia)
07/2011 - 09/2009
3Weight Gain
07/2011 - 09/2009
3Panic Disorder (Panic Attack)
07/2006 - 06/2004
2Disease Progression
12/2019 - 01/2013
2Cognitive Dysfunction
01/2019 - 01/2017
2Pain (Aches)
12/2015 - 03/2015
2Fibrosis (Cirrhosis)
12/2015 - 01/2011
2Anxiety Disorders (Anxiety Disorder)
01/2015 - 06/2014
2Genetic Predisposition to Disease (Genetic Predisposition)
04/2012 - 01/2012
2Neurobehavioral Manifestations
12/2010 - 03/2009

Drug/Important Bio-Agent (IBA)

18Antidepressive Agents (Antidepressants)IBA
04/2022 - 09/2009
18Biological ProductsIBA
01/2021 - 10/2002
12Nortriptyline (Aventyl)FDA LinkGeneric
01/2019 - 03/2009
12EscitalopramFDA Link
01/2019 - 03/2009
11LithiumIBA
07/2022 - 01/2013
11Antipsychotic Agents (Antipsychotics)IBA
03/2022 - 07/2002
10Pharmaceutical PreparationsIBA
11/2021 - 07/2011
9Biomarkers (Surrogate Marker)IBA
10/2022 - 01/2004
7N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
01/2016 - 10/2006
7D-Amino-Acid Oxidase (D-Amino Acid Dehydrogenase)IBA
06/2015 - 11/2005
7Neuregulin-1 (Neuregulin 1)IBA
05/2014 - 09/2006
6Hydrocortisone (Cortisol)FDA LinkGeneric
01/2022 - 05/2005
6DysbindinIBA
04/2012 - 01/2003
5Apolipoproteins E (ApoE)IBA
01/2021 - 01/2014
5ApolipoproteinsIBA
01/2021 - 01/2014
5salicylhydroxamic acid (SHAM)IBA
01/2021 - 06/2015
5Glucocorticoid Receptors (Glucocorticoid Receptor)IBA
09/2015 - 05/2005
5Serotonin (5 Hydroxytryptamine)IBA
01/2012 - 07/2006
4Proteins (Proteins, Gene)FDA Link
10/2019 - 07/2009
4Protein Isoforms (Isoforms)IBA
10/2018 - 03/2010
4Glutamic Acid (Glutamate)FDA Link
10/2018 - 10/2008
4Dopamine (Intropin)FDA LinkGeneric
12/2017 - 09/2006
4Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA
01/2015 - 05/2004
4Calcium Channels (Calcium Channel)IBA
07/2014 - 02/2014
3Glutamate Receptors (Glutamate Receptor)IBA
01/2022 - 10/2008
3Serotonin ReceptorsIBA
01/2020 - 11/2004
3GhrelinIBA
01/2019 - 11/2017
3C-Reactive ProteinIBA
10/2018 - 05/2017
3Catechol O-Methyltransferase (Methyltransferase, Catechol)IBA
01/2018 - 04/2012
3Transcription Factor 4IBA
07/2015 - 08/2009
3Tryptophan HydroxylaseIBA
11/2014 - 01/2008
3Brain-Derived Neurotrophic Factor (BDNF)IBA
08/2013 - 08/2005
3NeurocanIBA
09/2012 - 03/2011
3DNA (Deoxyribonucleic Acid)IBA
01/2012 - 09/2006
3Neurotransmitter Agents (Neurotransmitter)IBA
01/2008 - 04/2004
2HLA-DQB1 antigen (HLA DQB1)IBA
12/2021 - 01/2021
2Clozapine (Clozaril)FDA LinkGeneric
12/2021 - 01/2019
2Ethanol (Ethyl Alcohol)IBA
01/2021 - 05/2017
2Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA
01/2020 - 01/2019
2Glucose (Dextrose)FDA LinkGeneric
10/2019 - 03/2013
2Hormones (Hormone)IBA
01/2019 - 01/2019
2Oxidoreductases (Dehydrogenase)IBA
01/2019 - 07/2011
2EnzymesIBA
01/2019 - 07/2006
2Tricyclic Antidepressive Agents (Tricyclic Antidepressants)IBA
01/2019 - 04/2011
2ProlactinIBA
01/2019 - 01/2009
2LeptinIBA
01/2019 - 12/2017
2CalciumIBA
01/2018 - 01/2017
2Messenger RNA (mRNA)IBA
01/2017 - 06/2011
2Opioid Analgesics (Opioids)IBA
03/2016 - 08/2015
2Serine (L-Serine)FDA Link
01/2016 - 08/2008
2N-Methylaspartate (NMDA)IBA
01/2016 - 09/2013
2P-2 (P 2)IBA
11/2015 - 06/2012
2Dopa DecarboxylaseIBA
11/2014 - 07/2002
2Butyric Acid (Butanoic Acid)IBA
10/2014 - 02/2007
2Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA
03/2014 - 05/2007
2NicotineFDA Link
01/2014 - 08/2013
2Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
12/2013 - 08/2010
2glutamate receptor delta 1IBA
12/2012 - 06/2009
23' Untranslated Regions (3' UTR)IBA
01/2012 - 04/2007
2NeurograninIBA
10/2011 - 08/2009
2catechol (pyrocatechol)IBA
09/2010 - 06/2004
2TransferasesIBA
09/2010 - 06/2004
25-HT3 Serotonin Receptors (5 HT3 Receptor)IBA
06/2010 - 11/2009
2Clomipramine (Anafranil)FDA LinkGeneric
01/2009 - 07/2006
25-HT1A Serotonin ReceptorIBA
01/2009 - 06/2004
2serine racemaseIBA
04/2007 - 04/2007
2Phospholipases A2 (Phospholipase A2)IBA
08/2006 - 12/2003

Therapy/Procedure

4Therapeutics
12/2021 - 05/2017
4Transcranial Magnetic Stimulation
01/2019 - 06/2015
2Self Administration (Administration, Self)
01/2019 - 11/2017
2Behavior Control
01/2017 - 06/2015